Research Use Only: This product is supplied for laboratory research and in-vitro studies. Not for human or veterinary administration.
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Tesofensine Capsules (500mcg) 100 Count
Tesofensine Capsules (500mcg) 100 Count
- Profile: Tesofensine (NS2330) triple monoamine reuptake inhibitor
- Applications: Triple monoamine transporter (SERT/NET/DAT) pharmacology and binding kinetics
- Quality: >=95% Purity (HPLC Verified)
- Metabolic Synergy Research
- In-Vitro Receptor Profiling
- HPLC Verified (≥98% Purity)
$170.00In Stock
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Research Overview
Technical Specifications
| Characteristic | Value |
|---|---|
| CAS Number | 195875-84-4 |
| Molecular Weight | 328.28 |
| Storage | -20°C, protected from light and moisture |
Mechanism of Action
Tesofensine potently inhibits serotonin (SERT), norepinephrine (NET), and dopamine (DAT) transporters with IC₅₀ values of 11 nM, 1.7 nM, and 8 65 nM respectively. This triple reuptake inhibition increases synaptic monoamine concentrations, modulating lateral hypothalamic GABAergic neurons involved in feeding behavior through α1 adrenoceptor and dopamine D1 receptor pathway stimulation. The compoun
Research Applications
- Triple monoamine transporter (SERT/NET/DAT) pharmacology and binding kinetics
- Central appetite regulation and lateral hypothalamic neuron modulation research
- α1 adrenoceptor and dopamine D1 receptor pathway signaling studies
- Striatal dopamine D2/D3 receptor availability and reward pathway investigation
- Thermogenesis and energy expenditure mechanism research
- Long half-life pharmacokinetics and CYP3A4 metabolism studies